Security record · archived quarter
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Amicus Therapeutics, Inc. · Healthcare · Biotechnology
112Tracked holders
+4Δ holders
192.14MShares held
$2.74BReported value
+5New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +3.7% ·
share flow -11.9% ·
net new positions +4.5%
— formula
Ownership fragmentation — more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q1 2026 | 106 | -6 | 206.15M | $2.98B | +6 | −13 |
| Q4 2025 | 112 | +4 | 192.14M | $2.74B | +5 | — |
| Q3 2025 | 19 | -1 | 150.66M | $1.19B | — | −2 |
| Q2 2025 | 18 | 0 | 135.88M | $778.62M | — | — |
| Q1 2025 | 15 | +2 | 70.64M | $576.46M | +2 | — |
| Q4 2024 | 13 | -1 | 63.65M | $599.56M | — | −1 |
| Q3 2024 | 13 | +2 | 42.84M | $457.59M | +2 | — |
| Q2 2024 | 11 | — | 38.85M | $385.40M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | BlackRock ✦ (passive) | 32.52M | +25.8% | $463.15M | 0.0% | ▲ Add | 3 | SEC ↗ ×17 |
| 2 | The Vanguard Group ✦ (passive) | 29.70M | +0.6% | $422.97M | 0.0% | ▲ Add | 3 | SEC ↗ ×5 |
| 3 | State Street Global Advisors ✦ (passive) | 14.83M | +28.3% | $211.23M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 4 | Geode Capital Management ✦ (passive) | 7.35M | +3.5% | $104.62M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 5 | Goldman Sachs Group ✦ | 6.14M | +62.3% | $87.48M | 0.0% | ▲ Add | 2 | SEC ↗ ×4 |
| 6 | UBS Group AG | 5.89M | — | $83.92M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 7 | Morgan Stanley ✦ | 5.48M | +71.3% | $78.03M | 0.0% | ▲ Add | 2 | SEC ↗ ×7 |
| 8 | Balyasny Asset Management L.P. | 5.12M | — | $72.97M | 0.1% | n/c | 1 | SEC ↗ |
| 9 | Citadel Advisors ✦ | 5.10M | -38.2% | $72.58M | 0.1% | ▼ Trim | 7 | SEC ↗ ×2 |
| 10 | Nomura Asset Management… | 5.07M | — | $72.19M | 0.1% | n/c | 1 | SEC ↗ |
| 11 | Soros Fund Management ✦ | 5.00M | New | $71.20M | 1.3% | New | 1 | SEC ↗ |
| 12 | Nuveen, LLC | 4.63M | — | $65.91M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 13 | Qube Research & Technologies Ltd | 4.43M | — | $63.15M | 0.1% | n/c | 1 | SEC ↗ |
| 14 | JPMorgan Chase ✦ | 3.72M | -12.2% | $52.94M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 15 | Deutsche Bank Ag\ | 3.46M | — | $49.23M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 16 | Bank Of America Corp /De/ | 3.44M | — | $48.96M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 17 | Millennium Management ✦ | 3.00M | -74.6% | $42.65M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 18 | Alliancebernstein L.P. | 2.71M | — | $38.61M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Northern Trust Corp | 2.64M | — | $37.65M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 20 | Charles Schwab Investment… | 2.56M | — | $36.48M | 0.0% | n/c | 1 | SEC ↗ |
| 21 | Bnp Paribas Financial Markets | 2.25M | — | $32.06M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | Point72 Asset Management ✦ | 2.07M | -71.1% | $29.45M | 0.0% | ▼ Trim | 4 | SEC ↗ |
| 23 | Pictet Asset Management Holding SA | 1.99M | — | $28.43M | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Capstone Investment Advisors, Llc | 1.85M | — | $26.34M | 0.3% | n/c | 1 | SEC ↗ |
| 25 | Adage Capital Partners ✦ | 1.65M | New | $23.50M | 0.0% | New | 1 | SEC ↗ |
| 26 | Citigroup Inc | 1.65M | — | $23.48M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 27 | D. E. Shaw & Co. ✦ | 1.55M | -60.0% | $22.06M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 28 | Allianz Asset Management GmbH | 1.49M | — | $21.17M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 29 | Two Sigma Investments ✦ | 1.47M | +51.1% | $20.98M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 30 | Wellington Management ✦ | 1.37M | -95.2% | $19.56M | 0.0% | ▼ Trim | 7 | SEC ↗ ×5 |
| 31 | Invesco Ltd. | 1.26M | — | $17.93M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 32 | Connor, Clark & Lunn Investment… | 1.22M | — | $17.34M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Renaissance Technologies ✦ | 1.21M | -37.6% | $17.25M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 34 | Norges Bank ✦ (passive) | 1.17M | New | $16.59M | 0.0% | New | 1 | SEC ↗ |
| 35 | LMR Partners LLP | 1.16M | — | $16.48M | 0.2% | n/c | 1 | SEC ↗ ×2 |
| 36 | Barclays Plc | 1.13M | — | $16.16M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 37 | AQR Capital Management ✦ | 966.79K | +139.0% | $13.77M | 0.0% | ▲ Add | 7 | SEC ↗ ×6 |
| 38 | FIL Ltd | 957.00K | — | $13.63M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Tudor Investment Corp Et Al | 900.00K | — | $12.82M | 0.1% | n/c | 1 | SEC ↗ |
| 40 | UBS AM, a distinct business unit of… | 857.83K | — | $12.22M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 41 | Bank of New York Mellon Corp | 829.90K | — | $11.82M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 42 | Healthcare Of Ontario Pension Plan… | 800.00K | — | $11.39M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Jane Street Group, Llc | 726.80K | — | $10.35M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 44 | PRIMECAP Management ✦ | 589.40K | -11.8% | $8.39M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 45 | Swiss National Bank | 547.00K | — | $7.79M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | First Trust Advisors Lp | 533.51K | — | $7.60M | 0.0% | n/c | 1 | SEC ↗ |
| 47 | Creative Planning | 402.40K | — | $5.73M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 48 | Man Group plc | 400.00K | — | $5.70M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 49 | Principal Financial Group Inc | 399.51K | — | $5.69M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 50 | Rhumbline Advisers | 376.75K | — | $5.36M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Victory Capital Management Inc | 347.43K | — | $4.95M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Wells Fargo & Company/Mn | 339.43K | — | $4.83M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 53 | Canada Pension Plan Investment Board | 285.73K | — | $4.07M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Legal & General Group Plc | 283.01K | — | $4.03M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 55 | T. Rowe Price ✦ | 281.84K | -73.3% | $4.01M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 56 | Squarepoint Ops LLC | 269.30K | — | $3.83M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | California State Teachers… | 265.51K | — | $3.78M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Marshall Wace ✦ | 240.90K | New | $3.43M | 0.0% | New | 1 | SEC ↗ ×3 |
| 59 | Universal- Beteiligungs- und… | 231.34K | — | $3.29M | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Sei Investments Co | 216.92K | — | $3.09M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 61 | Walleye Trading LLC | 210.58K | — | $3.00M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | State Of Wisconsin Investment Board | 184.33K | — | $2.62M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Fidelity (FMR) ✦ | 178.43K | -64.6% | $2.54M | 0.0% | ▼ Trim | 3 | SEC ↗ ×2 |
| 64 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 167.24K | — | $2.38M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 65 | Manufacturers Life Insurance… | 145.44K | — | $2.07M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Susquehanna International Group, Llp | 144.76K | — | $2.06M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 67 | Gotham Asset Management ✦ | 139.55K | +0.7% | $1.99M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 68 | Janus Henderson Group Plc | 137.57K | — | $1.96M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 69 | Massachusetts Financial Services Co… | 125.52K | — | $1.79M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 70 | Voya Investment Management Llc | 107.43K | — | $1.53M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 71 | Franklin Resources Inc | 91.87K | — | $1.31M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 72 | ProShare Advisors LLC | 89.82K | — | $1.28M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | New York State Common Retirement… | 88.52K | — | $1.26M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | State Board Of Administration Of… | 88.12K | — | $1.25M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Zurcher Kantonalbank (Zurich… | 79.34K | — | $1.13M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Russell Investments Group, Ltd. | 74.17K | — | $1.06M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 77 | Cerity Partners LLC | 63.08K | — | $898,273 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 78 | Tidal Investments LLC | 51.16K | — | $728,461 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Cwm, Llc | 50.79K | — | $723,000 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Brown Advisory Inc | 45.52K | — | $648,276 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Lazard Asset Management Llc | 41.28K | — | $587,884 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Wealth Enhancement Advisory… | 37.33K | — | $533,015 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Mariner, LLC | 36.68K | — | $522,336 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | LPL Financial LLC | 35.80K | — | $509,863 | 0.0% | n/c | 1 | SEC ↗ |
| 85 | American Century Companies Inc | 34.99K | — | $498,258 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Quantinno Capital Management LP | 34.98K | — | $498,115 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Bridgewater Associates ✦ | 32.27K | New | $459,582 | 0.0% | New | 1 | SEC ↗ |
| 88 | Allspring Global Investments… | 27.06K | — | $386,175 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 89 | Bank Of Montreal /Can/ | 25.45K | — | $362,408 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 90 | Captrust Financial Advisors | 25.40K | — | $361,696 | 0.0% | n/c | 1 | SEC ↗ |
| 91 | Royal Bank Of Canada | 25.39K | — | $361,000 | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 92 | Prudential Financial Inc | 18.90K | — | $269,136 | 0.0% | n/c | 1 | SEC ↗ |
| 93 | Simplex Trading, Llc | 18.86K | — | $268,523 | 0.0% | n/c | 1 | SEC ↗ |
| 94 | Mackenzie Financial Corp | 17.45K | — | $248,116 | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Mercer Global Advisors Inc /Adv | 16.96K | — | $241,561 | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Envestnet Asset Management Inc | 16.24K | — | $231,258 | 0.0% | n/c | 1 | SEC ↗ |
| 97 | Mirae Asset Global Investments Co.… | 14.99K | — | $213,500 | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Sumitomo Mitsui Trust Group, Inc. | 14.85K | — | $211,464 | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Group One Trading Llc | 13.47K | — | $191,799 | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Cetera Investment Advisers | 13.05K | — | $185,779 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Soros Fund Management | $71.20M | 1.3% |
| Adage Capital Partners | $23.50M | 0.0% |
| Norges Bank | $16.59M | 0.0% |
| Marshall Wace | $3.43M | 0.0% |
| Bridgewater Associates | $459,582 | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 296 holders, 325.04M shares, $4.48B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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