Security record · archived quarter
DSGN
Design Therapeutics, Inc. · Healthcare · Biotechnology
59Tracked holders
+1Δ holders
16.55MShares held
$155.25MReported value
+1New positions
−0Exits
Momentum inputs (comparable managers):
holder breadth +1.7% ·
share flow +23.3% ·
net new positions +1.7%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 61 | +2 | 14.66M | $212.03M | +5 | −3 |
| Q1 2026 | 61 | +2 | 13.39M | $142.37M | +4 | −2 |
| Q4 2025 | 59 | +1 | 16.55M | $155.25M | +1 | n/a |
| Q3 2025 | 16 | +1 | 10.74M | $80.90M | +1 | n/a |
| Q2 2025 | 12 | -2 | 9.77M | $32.93M | n/a | −2 |
| Q1 2025 | 11 | +2 | 5.33M | $20.59M | +2 | n/a |
| Q4 2024 | 9 | -2 | 5.31M | $32.78M | n/a | −2 |
| Q3 2024 | 10 | -1 | 4.34M | $23.36M | n/a | −1 |
| Q2 2024 | 11 | n/a | 4.24M | $14.20M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Point72 Asset Management ✦ | 5.37M | +60.8% | $50.39M | 0.1% | ▲ Add | 7 | SEC ↗ |
| 2 | BlackRock ✦ (passive) | 2.12M | +3.6% | $19.86M | 0.0% | ▲ Add | 3 | SEC ↗ ×9 |
| 3 | The Vanguard Group ✦ (passive) | 1.63M | +13.0% | $15.30M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 4 | Fidelity (FMR) ✦ | 771.27K | +4.1% | $7.23M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 5 | Morgan Stanley ✦ | 702.31K | +299.1% | $6.59M | 0.0% | ▲ Add | 2 | SEC ↗ ×6 |
| 6 | Geode Capital Management ✦ (passive) | 679.59K | -2.3% | $6.38M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 7 | State Street Global Advisors ✦ (passive) | 647.64K | +2.1% | $6.07M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 8 | Citadel Advisors ✦ | 459.87K | -17.0% | $4.31M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 9 | D. E. Shaw & Co. ✦ | 438.89K | +17.6% | $4.12M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 10 | Invesco Ltd. | 305.76K | n/a | $2.87M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 11 | Dimensional Fund Advisors Lp | 297.92K | n/a | $2.80M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 12 | Renaissance Technologies ✦ | 287.10K | +4.7% | $2.69M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 13 | Northern Trust Corp | 286.57K | n/a | $2.69M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 14 | Goldman Sachs Group ✦ | 270.65K | +3.5% | $2.54M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 15 | Charles Schwab Investment… | 236.86K | n/a | $2.22M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | Jane Street Group, Llc | 226.51K | n/a | $2.12M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 17 | Marshall Wace ✦ | 225.53K | New | $2.12M | 0.0% | New | 1 | SEC ↗ ×2 |
| 18 | Millennium Management ✦ | 180.87K | +162.8% | $1.70M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 19 | Ameriprise Financial Inc | 158.38K | n/a | $1.49M | 0.0% | n/c | 1 | SEC ↗ |
| 20 | Nuveen, LLC | 125.26K | n/a | $1.17M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 21 | Raymond James Financial Inc | 109.76K | n/a | $1.03M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | Bnp Paribas Financial Markets | 94.83K | n/a | $889,487 | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Barclays Plc | 87.06K | n/a | $816,622 | 0.0% | n/c | 1 | SEC ↗ |
| 24 | Bank of New York Mellon Corp | 84.97K | n/a | $797,065 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 25 | Susquehanna International Group, Llp | 61.85K | n/a | $580,172 | 0.0% | n/c | 1 | SEC ↗ |
| 26 | American Century Companies Inc | 57.80K | n/a | $542,146 | 0.0% | n/c | 1 | SEC ↗ |
| 27 | Canada Pension Plan Investment Board | 54.60K | n/a | $512,148 | 0.0% | n/c | 1 | SEC ↗ |
| 28 | Corient Private Wealth LP | 53.93K | n/a | $505,864 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 29 | Sei Investments Co | 52.73K | n/a | $494,607 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 30 | State Of Wisconsin Investment Board | 50.66K | n/a | $475,163 | 0.0% | n/c | 1 | SEC ↗ |
| 31 | Two Sigma Investments ✦ | 46.24K | -21.9% | $433,703 | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 32 | Squarepoint Ops LLC | 46.14K | n/a | $432,812 | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Alliancebernstein L.P. | 46.12K | n/a | $432,606 | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Prudential Financial Inc | 42.71K | n/a | $400,620 | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Rhumbline Advisers | 34.78K | n/a | $326,208 | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Bank Of America Corp /De/ | 27.45K | n/a | $257,443 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 37 | Wells Fargo & Company/Mn | 26.79K | n/a | $251,253 | 0.0% | n/c | 1 | SEC ↗ |
| 38 | UBS Group AG | 25.54K | n/a | $239,537 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 39 | Russell Investments Group, Ltd. | 25.23K | n/a | $236,694 | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 40 | T. Rowe Price ✦ | 15.71K | -3.7% | $148,000 | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 41 | Deutsche Bank Ag\ | 15.54K | n/a | $145,775 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | JPMorgan Chase ✦ | 14.45K | -68.9% | $135,550 | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 43 | AQR Capital Management ✦ | 13.73K | +0.5% | $128,788 | 0.0% | ▲ Add | 7 | SEC ↗ ×6 |
| 44 | Mariner, LLC | 12.82K | n/a | $119,965 | 0.0% | n/c | 1 | SEC ↗ |
| 45 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 11.09K | n/a | $104,034 | 0.0% | n/c | 1 | SEC ↗ |
| 46 | Citigroup Inc | 3.11K | n/a | $29,200 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 47 | Mirae Asset Global Investments Co.… | 2.77K | n/a | $25,964 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Legal & General Group Plc | 2.08K | n/a | $19,482 | 0.0% | n/c | 1 | SEC ↗ |
| 49 | New York State Common Retirement… | 2.03K | n/a | $19,004 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Pnc Financial Services Group, Inc. | 1.82K | n/a | $17,035 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 51 | California State Teachers… | 1.47K | n/a | $13,798 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | Zurcher Kantonalbank (Zurich… | 1.23K | n/a | $11,509 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Rockefeller Capital Management L.P. | 738 | n/a | $6,922 | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Royal Bank Of Canada | 638 | n/a | $6,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 55 | UBS AM, a distinct business unit of… | 380 | n/a | $3,564 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Optiver Holding B.V. | 328 | n/a | $3,077 | 0.0% | n/c | 1 | SEC ↗ |
| 57 | Cwm, Llc | 239 | n/a | $2,000 | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Daiwa Securities Group Inc. | 100 | n/a | $1,000 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Osaic Holdings, Inc. | 10 | n/a | $94 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| Marshall Wace | $2.12M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 124 holders, 37.97M shares, $395.07M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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