ANNX
Annexon, Inc. · Healthcare · Biotechnology
Momentum inputs (comparable managers):
holder breadth +4.1% ·
share flow +16.7% ·
net new positions +3.9%
· formula
Broad accumulation: rising shares across more holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 83 | 0 | 98.98M | $564.98M | +7 | −7 |
| Q1 2026 | 86 | +9 | 86.15M | $477.02M | +15 | −6 |
| Q4 2025 | 77 | +3 | 76.53M | $384.12M | +3 | n/a |
| Q3 2025 | 16 | +1 | 41.50M | $126.59M | +2 | −1 |
| Q2 2025 | 12 | 0 | 37.67M | $90.40M | +2 | −2 |
| Q1 2025 | 9 | -2 | 6.64M | $12.81M | n/a | −2 |
| Q4 2024 | 11 | -2 | 14.57M | $74.72M | n/a | −2 |
| Q3 2024 | 12 | +1 | 12.67M | $75.00M | +1 | n/a |
| Q2 2024 | 11 | n/a | 15.25M | $74.74M | n/a | n/a |
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Fidelity (FMR) ✦ | 10.22M | -7.8% | $51.32M | 0.0% | ▼ Trim | 3 | SEC ↗ ×4 |
| 2 | BlackRock ✦ (passive) | 8.96M | +13.4% | $44.98M | 0.0% | ▲ Add | 3 | SEC ↗ ×10 |
| 3 | The Vanguard Group ✦ (passive) | 7.75M | +32.9% | $38.92M | 0.0% | ▲ Add | 3 | SEC ↗ ×3 |
| 4 | Adage Capital Partners ✦ | 5.50M | +266.7% | $27.61M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 5 | State Street Global Advisors ✦ (passive) | 4.65M | +126.9% | $23.35M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 6 | Ameriprise Financial Inc | 4.35M | n/a | $21.83M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 7 | Balyasny Asset Management L.P. | 3.30M | n/a | $16.56M | 0.0% | n/c | 1 | SEC ↗ |
| 8 | Nuveen, LLC | 2.92M | n/a | $14.63M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 9 | Geode Capital Management ✦ (passive) | 2.90M | +19.1% | $14.58M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 10 | Morgan Stanley ✦ | 2.86M | -5.7% | $14.34M | 0.0% | ▼ Trim | 2 | SEC ↗ ×6 |
| 11 | Millennium Management ✦ | 2.84M | +0.5% | $14.24M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 12 | Qube Research & Technologies Ltd | 2.38M | n/a | $11.96M | 0.0% | n/c | 1 | SEC ↗ |
| 13 | Goldman Sachs Group ✦ | 1.77M | -26.5% | $8.88M | 0.0% | ▼ Trim | 2 | SEC ↗ ×3 |
| 14 | Bank Of America Corp /De/ | 1.61M | n/a | $8.06M | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 15 | Charles Schwab Investment… | 1.06M | n/a | $5.31M | 0.0% | n/c | 1 | SEC ↗ |
| 16 | D. E. Shaw & Co. ✦ | 1.05M | New | $5.25M | 0.0% | New | 1 | SEC ↗ ×2 |
| 17 | Invesco Ltd. | 972.45K | n/a | $4.88M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 18 | Massachusetts Financial Services Co… | 903.44K | n/a | $4.54M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Renaissance Technologies ✦ | 802.60K | +6.5% | $4.03M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 20 | Northern Trust Corp | 792.00K | n/a | $3.98M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 21 | AQR Capital Management ✦ | 776.31K | +35.2% | $3.90M | 0.0% | ▲ Add | 7 | SEC ↗ ×6 |
| 22 | Dimensional Fund Advisors Lp | 718.68K | n/a | $3.61M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 23 | Russell Investments Group, Ltd. | 683.02K | n/a | $3.43M | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 24 | Wells Fargo & Company/Mn | 573.75K | n/a | $2.88M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 25 | Deutsche Bank Ag\ | 560.74K | n/a | $2.81M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 26 | Marshall Wace ✦ | 521.00K | New | $2.62M | 0.0% | New | 1 | SEC ↗ ×2 |
| 27 | Jane Street Group, Llc | 513.84K | n/a | $2.58M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 28 | T. Rowe Price ✦ | 445.07K | -8.2% | $2.23M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 29 | Wellington Management ✦ | 398.08K | New | $2.00M | 0.0% | New | 1 | SEC ↗ ×3 |
| 30 | UBS Group AG | 377.10K | n/a | $1.89M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 31 | Point72 Asset Management ✦ | 371.19K | +312.2% | $1.86M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 32 | Bank of New York Mellon Corp | 361.68K | n/a | $1.82M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 33 | Two Sigma Investments ✦ | 332.04K | +18.9% | $1.67M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 34 | Barclays Plc | 289.96K | n/a | $1.46M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 35 | Citadel Advisors ✦ | 275.29K | +64.3% | $1.38M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 36 | American Century Companies Inc | 251.16K | n/a | $1.26M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Susquehanna International Group, Llp | 185.51K | n/a | $931,250 | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Osaic Holdings, Inc. | 147.38K | n/a | $739,822 | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Alliancebernstein L.P. | 140.74K | n/a | $706,515 | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Manufacturers Life Insurance… | 130.10K | n/a | $655,094 | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Rhumbline Advisers | 126.46K | n/a | $634,834 | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Bnp Paribas Financial Markets | 61.57K | n/a | $309,091 | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Sei Investments Co | 58.26K | n/a | $292,460 | 0.0% | n/c | 1 | SEC ↗ |
| 44 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 54.76K | n/a | $275,076 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 45 | JPMorgan Chase ✦ | 53.73K | -42.7% | $269,719 | 0.0% | ▼ Trim | 2 | SEC ↗ ×4 |
| 46 | Hsbc Holdings Plc | 51.30K | n/a | $260,358 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 47 | Td Asset Management Inc | 46.85K | n/a | $235,177 | 0.0% | n/c | 1 | SEC ↗ |
| 48 | Corient Private Wealth LP | 39.39K | n/a | $197,718 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 49 | Captrust Financial Advisors | 31.59K | n/a | $158,557 | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Mariner, LLC | 31.34K | n/a | $157,351 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 51 | Cwm, Llc | 30.30K | n/a | $152,000 | 0.0% | n/c | 1 | SEC ↗ |
| 52 | New York State Common Retirement… | 29.57K | n/a | $148,431 | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Raymond James Financial Inc | 24.87K | n/a | $124,842 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 54 | ProShare Advisors LLC | 24.70K | n/a | $123,984 | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Creative Planning | 24.00K | n/a | $120,500 | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Citigroup Inc | 23.64K | n/a | $118,673 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 57 | Lido Advisors, LLC | 34.95K | n/a | $106,604 | 0.0% | n/c | 1 | SEC ↗ |
| 58 | Wealth Enhancement Advisory… | 19.55K | n/a | $99,720 | 0.0% | n/c | 1 | SEC ↗ |
| 59 | Voya Investment Management Llc | 19.32K | n/a | $96,976 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | Canada Pension Plan Investment Board | 17.60K | n/a | $88,352 | 0.0% | n/c | 1 | SEC ↗ |
| 61 | Cerity Partners LLC | 14.80K | n/a | $74,301 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 62 | Victory Capital Management Inc | 14.76K | n/a | $74,080 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Group One Trading Llc | 14.18K | n/a | $71,204 | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Mercer Global Advisors Inc /Adv | 10.39K | n/a | $52,138 | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Simplex Trading, Llc | 10.27K | n/a | $51,545 | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Legal & General Group Plc | 9.31K | n/a | $46,721 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Mirae Asset Global Investments Co.… | 7.03K | n/a | $35,306 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | California State Teachers… | 6.16K | n/a | $30,938 | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Royal Bank Of Canada | 2.85K | n/a | $15,000 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 70 | Jones Financial Companies Lllp | 2.99K | n/a | $14,995 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Pnc Financial Services Group, Inc. | 1.13K | n/a | $5,683 | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 72 | Federated Hermes, Inc. | 753 | n/a | $3,780 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Optiver Holding B.V. | 530 | n/a | $2,661 | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Daiwa Securities Group Inc. | 352 | n/a | $2,000 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Rockefeller Capital Management L.P. | 334 | n/a | $1,677 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Assetmark, Inc | 333 | n/a | $1,672 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Northwestern Mutual Wealth… | 4 | n/a | $20 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| D. E. Shaw & Co. | $5.25M | 0.0% |
| Marshall Wace | $2.62M | 0.0% |
| Wellington Management | $2.00M | 0.0% |
Exited
| No tracked exits this quarter. |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 216 holders, 155.62M shares, $854.15M reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Open-market purchases (P)
Officer, Director · PRESIDENT AND CEO · 26.07K sh @ 3.83 · $99,829
Open-market sales (S)
No open-market insider sales in our coverage window.
Awards, exercises and tax withholding are never counted as buys or sales here. Methodology