Security record · archived quarter
AGIO
Agios Pharmaceuticals, Inc. · Healthcare · Biotechnology
89Tracked holders
-2Δ holders
38.17MShares held
$1.04BReported value
+0New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -2.2% ·
share flow +2.1% ·
net new positions -2.2%
· formula
Concentrated accumulation: rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q3 2026 | 2 | 0 | 1.91M | $63.34M | n/a | n/a |
| Q2 2026 | 89 | +3 | 38.62M | $1.43B | +11 | −8 |
| Q1 2026 | 89 | 0 | 33.63M | $1.14B | +5 | −5 |
| Q4 2025 | 89 | -2 | 38.17M | $1.04B | n/a | −2 |
| Q3 2025 | 19 | +2 | 22.49M | $902.53M | +2 | −1 |
| Q2 2025 | 15 | 0 | 21.02M | $699.20M | n/a | n/a |
| Q1 2025 | 12 | -1 | 9.99M | $292.81M | n/a | −1 |
| Q4 2024 | 13 | +2 | 10.10M | $332.03M | +2 | n/a |
| Q3 2024 | 10 | 0 | 7.27M | $323.20M | n/a | n/a |
| Q2 2024 | 10 | n/a | 7.12M | $306.93M | n/a | n/a |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ ×5 |
| 2 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ ×15 |
| 3 | State Street Global Advisors ✦ (passive) | 3.11M | +37.4% | $84.60M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 4 | D. E. Shaw & Co. ✦ | 1.84M | +399.6% | $50.01M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 5 | Nomura Asset Management… | 1.70M | n/a | $46.31M | 0.1% | n/c | 1 | SEC ↗ |
| 6 | Geode Capital Management ✦ (passive) | 1.41M | -0.2% | $38.48M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 7 | BNP Paribas Asset Management… | 1.36M | n/a | $37.04M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 8 | Citadel Advisors ✦ | 1.35M | +174.2% | $36.72M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 9 | Susquehanna International Group, Llp | 1.14M | n/a | $31.10M | 0.0% | n/c | 1 | SEC ↗ |
| 10 | Jane Street Group, Llc | 1.12M | n/a | $30.51M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 11 | Goldman Sachs Group ✦ | 1.03M | +28.5% | $28.14M | 0.0% | ▲ Add | 2 | SEC ↗ ×2 |
| 12 | Dimensional Fund Advisors Lp | 1.00M | n/a | $27.34M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 13 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ ×8 |
| 14 | Capital International Investors | 703.87K | n/a | $19.16M | 0.0% | n/c | 1 | SEC ↗ |
| 15 | T. Rowe Price ✦ | 637.89K | -61.5% | $17.36M | 0.0% | ▼ Trim | 7 | SEC ↗ ×2 |
| 16 | Balyasny Asset Management L.P. | 635.07K | n/a | $17.29M | 0.0% | n/c | 1 | SEC ↗ |
| 17 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ ×6 |
| 18 | Connor, Clark & Lunn Investment… | 562.64K | n/a | $15.32M | 0.0% | n/c | 1 | SEC ↗ |
| 19 | Bank Of America Corp /De/ | 539.34K | n/a | $14.68M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 20 | Northern Trust Corp | 511.90K | n/a | $13.93M | 0.0% | n/c | 1 | SEC ↗ ×6 |
| 21 | Artisan Partners Limited Partnership | 504.49K | n/a | $13.73M | 0.0% | n/c | 1 | SEC ↗ |
| 22 | Charles Schwab Investment… | 482.62K | n/a | $13.14M | 0.0% | n/c | 1 | SEC ↗ |
| 23 | Millennium Management ✦ | 398.27K | +7788.0% | $10.84M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 24 | Qube Research & Technologies Ltd | 378.37K | n/a | $10.30M | 0.0% | n/c | 1 | SEC ↗ |
| 25 | Marshall Wace ✦ | 353.64K | +55.9% | $9.63M | 0.0% | ▲ Add | 7 | SEC ↗ ×2 |
| 26 | Legal & General Group Plc | 328.21K | n/a | $8.93M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 27 | Barclays Plc | 320.35K | n/a | $8.72M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 28 | Two Sigma Investments ✦ | 300.16K | +403.4% | $8.17M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 29 | Nuveen, LLC | 297.91K | n/a | $8.11M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 30 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ ×5 |
| 31 | Bnp Paribas Financial Markets | 242.67K | n/a | $6.61M | 0.0% | n/c | 1 | SEC ↗ |
| 32 | Pictet Asset Management Holding SA | 205.02K | n/a | $5.57M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Point72 Asset Management ✦ | 200.00K | +2973.6% | $5.44M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 34 | Bank of New York Mellon Corp | 196.89K | n/a | $5.36M | 0.0% | n/c | 1 | SEC ↗ ×7 |
| 35 | Group One Trading Llc | 166.61K | n/a | $4.54M | 0.1% | n/c | 1 | SEC ↗ |
| 36 | American Century Companies Inc | 151.49K | n/a | $4.12M | 0.0% | n/c | 1 | SEC ↗ |
| 37 | Allianz Asset Management GmbH | 147.95K | n/a | $4.03M | 0.0% | n/c | 1 | SEC ↗ |
| 38 | Hrt Financial Lp | 146.47K | n/a | $3.99M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Invesco Ltd. | 142.58K | n/a | $3.88M | 0.0% | n/c | 1 | SEC ↗ ×5 |
| 40 | UBS Group AG | 126.67K | n/a | $3.45M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 41 | Deutsche Bank Ag\ | 122.88K | n/a | $3.34M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 42 | Squarepoint Ops LLC | 121.76K | n/a | $3.31M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Assenagon Asset Management S.A. | 110.44K | n/a | $3.01M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Swiss National Bank | 108.86K | n/a | $2.96M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | UBS AM, a distinct business unit of… | 107.00K | n/a | $2.91M | 0.0% | n/c | 1 | SEC ↗ ×9 |
| 46 | Citigroup Inc | 88.24K | n/a | $2.40M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 47 | Prudential Financial Inc | 81.06K | n/a | $2.21M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 48 | First Trust Advisors Lp | 78.66K | n/a | $2.14M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | Rhumbline Advisers | 74.15K | n/a | $2.02M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | Manufacturers Life Insurance… | 70.26K | n/a | $1.92M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | Wells Fargo & Company/Mn | 64.77K | n/a | $1.76M | 0.0% | n/c | 1 | SEC ↗ ×3 |
| 52 | Alliancebernstein L.P. | 61.49K | n/a | $1.67M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | Tudor Investment Corp Et Al | 61.34K | n/a | $1.67M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | Universal- Beteiligungs- und… | 60.56K | n/a | $1.65M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Td Asset Management Inc | 57.29K | n/a | $1.56M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | California State Teachers… | 53.24K | n/a | $1.45M | 0.0% | n/c | 1 | SEC ↗ |
| 57 | New York State Common Retirement… | 51.71K | n/a | $1.41M | 0.0% | n/c | 1 | SEC ↗ |
| 58 | MIRAE ASSET GLOBAL ETFS HOLDINGS… | 39.45K | n/a | $1.07M | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 59 | State Of Wisconsin Investment Board | 34.64K | n/a | $942,819 | 0.0% | n/c | 1 | SEC ↗ |
| 60 | AQR Capital Management ✦ | 27.93K | -69.5% | $754,002 | 0.0% | ▼ Trim | 7 | SEC ↗ ×6 |
| 61 | Victory Capital Management Inc | 27.70K | n/a | $753,912 | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Quantinno Capital Management LP | 26.86K | n/a | $730,993 | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Federated Hermes, Inc. | 25.05K | n/a | $681,997 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 64 | Russell Investments Group, Ltd. | 24.68K | n/a | $671,759 | 0.0% | n/c | 1 | SEC ↗ ×8 |
| 65 | Fidelity (FMR) ✦ | 24.33K | +17.5% | $662,380 | 0.0% | ▲ Add | 3 | SEC ↗ ×2 |
| 66 | Janus Henderson Group Plc | 23.80K | n/a | $648,230 | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Zurcher Kantonalbank (Zurich… | 23.62K | n/a | $642,936 | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Rockefeller Capital Management L.P. | 21.07K | n/a | $573,553 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 69 | Canada Pension Plan Investment Board | 18.20K | n/a | $495,404 | 0.0% | n/c | 1 | SEC ↗ |
| 70 | State Board Of Administration Of… | 15.85K | n/a | $431,355 | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Sei Investments Co | 14.35K | n/a | $390,680 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 72 | Tidal Investments LLC | 14.25K | n/a | $387,803 | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Royal Bank Of Canada | 13.05K | n/a | $354,000 | 0.0% | n/c | 1 | SEC ↗ ×4 |
| 74 | ProShare Advisors LLC | 12.90K | n/a | $351,057 | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Envestnet Asset Management Inc | 12.73K | n/a | $346,647 | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Nomura Holdings Inc | 12.36K | n/a | $336,303 | 0.0% | n/c | 1 | SEC ↗ |
| 77 | Creative Planning | 10.37K | n/a | $282,271 | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Capstone Investment Advisors, Llc | 10.36K | n/a | $281,863 | 0.0% | n/c | 1 | SEC ↗ |
| 79 | Voya Investment Management Llc | 10.13K | n/a | $275,847 | 0.0% | n/c | 1 | SEC ↗ |
| 80 | Ensign Peak Advisors, Inc | 6.57K | n/a | $178,835 | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Simplex Trading, Llc | 6.21K | n/a | $169,008 | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Pnc Financial Services Group, Inc. | 4.71K | n/a | $128,206 | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Mirae Asset Global Investments Co.… | 2.83K | n/a | $77,141 | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Osaic Holdings, Inc. | 1.75K | n/a | $47,553 | 0.0% | n/c | 1 | SEC ↗ ×2 |
| 85 | Assetmark, Inc | 1.32K | n/a | $35,849 | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Us Bancorp \De\ | 509 | n/a | $13,855 | 0.0% | n/c | 1 | SEC ↗ |
| 87 | Cwm, Llc | 484 | n/a | $13,000 | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Daiwa Securities Group Inc. | 204 | n/a | $6,000 | 0.0% | n/c | 1 | SEC ↗ |
| 89 | Jones Financial Companies Lllp | 1 | n/a | $27 | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value: the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Fisher Asset Management | $34.93M | was 0.0% |
| Adage Capital Partners | $32.11M | was 0.1% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 231 holders, 62.89M shares, $1.99B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold: shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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