Security record · archived quarter
AGIO
Agios Pharmaceuticals, Inc. · Healthcare · Biotechnology
89Tracked holders
-2Δ holders
38.17MShares held
$1.04BReported value
+0New positions
−2Exits
Momentum inputs (comparable managers):
holder breadth -2.2% ·
share flow +2.1% ·
net new positions -2.2%
— formula
Concentrated accumulation — rising shares among fewer holders
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q4 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 89 | +3 | 38.62M | $1.43B | +11 | −8 |
| Q1 2026 | 89 | 0 | 33.63M | $1.14B | +5 | −5 |
| Q4 2025 | 89 | -2 | 38.17M | $1.04B | — | −2 |
| Q3 2025 | 19 | +2 | 22.49M | $902.53M | +2 | −1 |
| Q2 2025 | 15 | 0 | 21.02M | $699.20M | — | — |
| Q1 2025 | 12 | -1 | 9.99M | $292.81M | — | −1 |
| Q4 2024 | 13 | +2 | 10.10M | $332.03M | +2 | — |
| Q3 2024 | 10 | 0 | 7.27M | $323.20M | — | — |
| Q2 2024 | 10 | — | 7.12M | $306.93M | — | — |
Who holds it · Q4 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 2 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 3 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 4 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 5 | The Vanguard Group ✦ (passive) | 5.59M | -0.2% | $152.28M | 0.0% | ▼ Trim | 3 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 19 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 20 | BlackRock ✦ (passive) | 5.24M | +15.2% | $142.51M | 0.0% | ▲ Add | 3 | SEC ↗ |
| 21 | State Street Global Advisors ✦ (passive) | 3.11M | +37.4% | $84.60M | 0.0% | ▲ Add | 5 | SEC ↗ |
| 22 | D. E. Shaw & Co. ✦ | 1.84M | +399.6% | $50.01M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 23 | D. E. Shaw & Co. ✦ | 1.84M | +399.6% | $50.01M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 24 | Nomura Asset Management… | 1.70M | — | $46.31M | 0.1% | n/c | 1 | SEC ↗ |
| 25 | Geode Capital Management ✦ (passive) | 1.41M | -0.2% | $38.48M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 26 | Geode Capital Management ✦ (passive) | 1.41M | -0.2% | $38.48M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 27 | BNP Paribas Asset Management… | 1.36M | — | $37.04M | 0.0% | n/c | 1 | SEC ↗ |
| 28 | BNP Paribas Asset Management… | 1.36M | — | $37.04M | 0.0% | n/c | 1 | SEC ↗ |
| 29 | BNP Paribas Asset Management… | 1.36M | — | $37.04M | 0.0% | n/c | 1 | SEC ↗ |
| 30 | Citadel Advisors ✦ | 1.35M | +174.2% | $36.72M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 31 | Citadel Advisors ✦ | 1.35M | +174.2% | $36.72M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 32 | Susquehanna International Group, Llp | 1.14M | — | $31.10M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Jane Street Group, Llc | 1.12M | — | $30.51M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Jane Street Group, Llc | 1.12M | — | $30.51M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Jane Street Group, Llc | 1.12M | — | $30.51M | 0.0% | n/c | 1 | SEC ↗ |
| 36 | Goldman Sachs Group ✦ | 1.03M | +28.5% | $28.14M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 37 | Goldman Sachs Group ✦ | 1.03M | +28.5% | $28.14M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 38 | Dimensional Fund Advisors Lp | 1.00M | — | $27.34M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Dimensional Fund Advisors Lp | 1.00M | — | $27.34M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Dimensional Fund Advisors Lp | 1.00M | — | $27.34M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Dimensional Fund Advisors Lp | 1.00M | — | $27.34M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Dimensional Fund Advisors Lp | 1.00M | — | $27.34M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 44 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 45 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 46 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 47 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 48 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 49 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 50 | Morgan Stanley ✦ | 894.04K | +114.4% | $24.34M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 51 | Capital International Investors | 703.87K | — | $19.16M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | T. Rowe Price ✦ | 637.89K | -61.5% | $17.36M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 53 | T. Rowe Price ✦ | 637.89K | -61.5% | $17.36M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 54 | Balyasny Asset Management L.P. | 635.07K | — | $17.29M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 56 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 57 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 58 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 59 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 60 | Wellington Management ✦ | 597.83K | -75.8% | $16.27M | 0.0% | ▼ Trim | 7 | SEC ↗ |
| 61 | Connor, Clark & Lunn Investment… | 562.64K | — | $15.32M | 0.0% | n/c | 1 | SEC ↗ |
| 62 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 63 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 64 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 65 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 66 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 67 | Bank Of America Corp /De/ | 539.34K | — | $14.68M | 0.0% | n/c | 1 | SEC ↗ |
| 68 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 69 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 70 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 71 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 72 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 73 | Northern Trust Corp | 511.90K | — | $13.93M | 0.0% | n/c | 1 | SEC ↗ |
| 74 | Artisan Partners Limited Partnership | 504.49K | — | $13.73M | 0.0% | n/c | 1 | SEC ↗ |
| 75 | Charles Schwab Investment… | 482.62K | — | $13.14M | 0.0% | n/c | 1 | SEC ↗ |
| 76 | Millennium Management ✦ | 398.27K | +7788.0% | $10.84M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 77 | Qube Research & Technologies Ltd | 378.37K | — | $10.30M | 0.0% | n/c | 1 | SEC ↗ |
| 78 | Marshall Wace ✦ | 353.64K | +55.9% | $9.63M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 79 | Marshall Wace ✦ | 353.64K | +55.9% | $9.63M | 0.0% | ▲ Add | 7 | SEC ↗ |
| 80 | Legal & General Group Plc | 328.21K | — | $8.93M | 0.0% | n/c | 1 | SEC ↗ |
| 81 | Legal & General Group Plc | 328.21K | — | $8.93M | 0.0% | n/c | 1 | SEC ↗ |
| 82 | Legal & General Group Plc | 328.21K | — | $8.93M | 0.0% | n/c | 1 | SEC ↗ |
| 83 | Barclays Plc | 320.35K | — | $8.72M | 0.0% | n/c | 1 | SEC ↗ |
| 84 | Barclays Plc | 320.35K | — | $8.72M | 0.0% | n/c | 1 | SEC ↗ |
| 85 | Barclays Plc | 320.35K | — | $8.72M | 0.0% | n/c | 1 | SEC ↗ |
| 86 | Two Sigma Investments ✦ | 300.16K | +403.4% | $8.17M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 87 | Nuveen, LLC | 297.91K | — | $8.11M | 0.0% | n/c | 1 | SEC ↗ |
| 88 | Nuveen, LLC | 297.91K | — | $8.11M | 0.0% | n/c | 1 | SEC ↗ |
| 89 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 90 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 91 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 92 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 93 | JPMorgan Chase ✦ | 251.78K | -31.2% | $6.85M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 94 | Bnp Paribas Financial Markets | 242.67K | — | $6.61M | 0.0% | n/c | 1 | SEC ↗ |
| 95 | Pictet Asset Management Holding SA | 205.02K | — | $5.57M | 0.0% | n/c | 1 | SEC ↗ |
| 96 | Point72 Asset Management ✦ | 200.00K | +2973.6% | $5.44M | 0.0% | ▲ Add | 2 | SEC ↗ |
| 97 | Bank of New York Mellon Corp | 196.89K | — | $5.36M | 0.0% | n/c | 1 | SEC ↗ |
| 98 | Bank of New York Mellon Corp | 196.89K | — | $5.36M | 0.0% | n/c | 1 | SEC ↗ |
| 99 | Bank of New York Mellon Corp | 196.89K | — | $5.36M | 0.0% | n/c | 1 | SEC ↗ |
| 100 | Bank of New York Mellon Corp | 196.89K | — | $5.36M | 0.0% | n/c | 1 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| No new tracked buyers this quarter. |
Exited
| Fisher Asset Management | $34.93M | was 0.0% |
| Adage Capital Partners | $32.11M | was 0.1% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 231 holders, 62.89M shares, $1.99B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q4 2025 ·
Methodology ·
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