Security record · archived quarter
AGIO
Agios Pharmaceuticals, Inc. · Healthcare · Biotechnology
19Tracked holders
+2Δ holders
22.49MShares held
$902.53MReported value
+2New positions
−1Exits
Momentum inputs (comparable managers):
holder breadth +11.8% ·
share flow -0.5% ·
net new positions +5.3%
— formula
Ownership fragmentation — more holders, smaller aggregate stake
All ownership figures: tracked 13F managers only, common-stock positions, reporting period Q3 2025
Ownership over time
| Quarter | Holders | Δ | Shares | Reported value | New | Exits |
|---|---|---|---|---|---|---|
| Q2 2026 | 89 | +3 | 38.62M | $1.43B | +11 | −8 |
| Q1 2026 | 89 | 0 | 33.63M | $1.14B | +5 | −5 |
| Q4 2025 | 89 | -2 | 38.17M | $1.04B | — | −2 |
| Q3 2025 | 19 | +2 | 22.49M | $902.53M | +2 | −1 |
| Q2 2025 | 15 | 0 | 21.02M | $699.20M | — | — |
| Q1 2025 | 12 | -1 | 9.99M | $292.81M | — | −1 |
| Q4 2024 | 13 | +2 | 10.10M | $332.03M | +2 | — |
| Q3 2024 | 10 | 0 | 7.27M | $323.20M | — | — |
| Q2 2024 | 10 | — | 7.12M | $306.93M | — | — |
Who holds it · Q3 2025
| # | Manager | Shares | Δ shares | Value | Their weight | Held | ||
|---|---|---|---|---|---|---|---|---|
| 1 | The Vanguard Group ✦ (passive) | 5.60M | -1.4% | $224.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 2 | The Vanguard Group ✦ (passive) | 5.60M | -1.4% | $224.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 3 | The Vanguard Group ✦ (passive) | 5.60M | -1.4% | $224.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 4 | The Vanguard Group ✦ (passive) | 5.60M | -1.4% | $224.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 5 | The Vanguard Group ✦ (passive) | 5.60M | -1.4% | $224.98M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 6 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 7 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 8 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 9 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 10 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 11 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 12 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 13 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 14 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 15 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 16 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 17 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 18 | BlackRock ✦ (passive) | 4.55M | -6.0% | $182.47M | 0.0% | ▼ Trim | 2 | SEC ↗ |
| 19 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 20 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 21 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 22 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 23 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 24 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 25 | Wellington Management ✦ | 2.47M | +485.5% | $99.20M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 26 | State Street Global Advisors ✦ (passive) | 2.26M | +16.0% | $90.83M | 0.0% | ▲ Add | 4 | SEC ↗ |
| 27 | T. Rowe Price ✦ | 1.66M | -27.1% | $66.51M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 28 | T. Rowe Price ✦ | 1.66M | -27.1% | $66.51M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 29 | Geode Capital Management ✦ (passive) | 1.42M | +0.8% | $56.86M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 30 | Geode Capital Management ✦ (passive) | 1.42M | +0.8% | $56.86M | 0.0% | ▲ Add | 6 | SEC ↗ |
| 31 | Fisher Asset Management ✦ | 870.14K | -0.8% | $34.93M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 32 | Goldman Sachs Group ✦ | 804.77K | — | $32.30M | 0.0% | n/c | 1 | SEC ↗ |
| 33 | Goldman Sachs Group ✦ | 804.77K | — | $32.30M | 0.0% | n/c | 1 | SEC ↗ |
| 34 | Goldman Sachs Group ✦ | 804.77K | — | $32.30M | 0.0% | n/c | 1 | SEC ↗ |
| 35 | Adage Capital Partners ✦ | 800.00K | +1.1% | $32.11M | 0.1% | ▲ Add | 4 | SEC ↗ |
| 36 | Citadel Advisors ✦ | 491.98K | -54.5% | $19.75M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 37 | Citadel Advisors ✦ | 491.98K | -54.5% | $19.75M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 38 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 39 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 40 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 41 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 42 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 43 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 44 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 45 | Morgan Stanley ✦ | 417.00K | — | $16.74M | 0.0% | n/c | 1 | SEC ↗ |
| 46 | D. E. Shaw & Co. ✦ | 367.75K | -38.3% | $14.76M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 47 | D. E. Shaw & Co. ✦ | 367.75K | -38.3% | $14.76M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 48 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 49 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 50 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 51 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 52 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 53 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 54 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 55 | JPMorgan Chase ✦ | 366.20K | — | $14.70M | 0.0% | n/c | 1 | SEC ↗ |
| 56 | Marshall Wace ✦ | 226.82K | -66.9% | $9.10M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 57 | AQR Capital Management ✦ | 91.64K | -5.4% | $3.61M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 58 | AQR Capital Management ✦ | 91.64K | -5.4% | $3.61M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 59 | AQR Capital Management ✦ | 91.64K | -5.4% | $3.61M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 60 | AQR Capital Management ✦ | 91.64K | -5.4% | $3.61M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 61 | AQR Capital Management ✦ | 91.64K | -5.4% | $3.61M | 0.0% | ▼ Trim | 6 | SEC ↗ |
| 62 | Two Sigma Investments ✦ | 59.63K | New | $2.39M | 0.0% | New | 1 | SEC ↗ |
| 63 | Fidelity (FMR) ✦ | 20.71K | +11.4% | $831,364 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 64 | Fidelity (FMR) ✦ | 20.71K | +11.4% | $831,364 | 0.0% | ▲ Add | 2 | SEC ↗ |
| 65 | Point72 Asset Management ✦ | 6.51K | New | $261,190 | 0.0% | New | 1 | SEC ↗ |
| 66 | Millennium Management ✦ | 5.05K | -98.3% | $202,667 | 0.0% | ▼ Trim | 6 | SEC ↗ |
“Their weight” = the position's share of that manager's reported 13F equity value — the conviction measure. ✦ = curated manager.
New buyers
| Two Sigma Investments | $2.39M | 0.0% |
| Point72 Asset Management | $261,190 | 0.0% |
Exited
| Norges Bank | $224,705 | was 0.0% |
Full-market context: across ALL 13F filers (SEC structured data, Q1 2026): 231 holders, 62.89M shares, $1.99B reported. This is a different, older period than the tracked-universe figures above and the two are never mixed.
Frequently co-owned
What else this security's tracked holders most often hold — shared-ownership counts, not fundamental relationships.
Provenance: Ownership from parsed 13F common-stock positions (tracked universe, comparable sets for changes); insider rows from Forms 3/4/5; stakes from Schedules 13D/13G; every filing links to its original on SEC EDGAR.
Reporting period: Q3 2025 ·
Methodology ·
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