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Manager record

Opaleye Management Inc.

Boston, MA · CIK 1595855 · EDGAR filings ↗

Cover-page record — Trade Filings parses every position for its tracked managers; for this filer it indexes the cover-page totals of each quarterly 13F report on SEC EDGAR.

$1.10BReported 13F valueQ2 2026 · as filed
58Holdings listed
+45.4%vs prior quartervalue change includes market moves
5Quarters on record
Aug 14Latest filed
Reported 13F value by quarter, Q2 2025 to Q2 2026Q2 2025: $494.1M$494.1MQ2 202541 holdingsQ3 2025: $707.3M$707.3MQ3 202543 holdingsQ4 2025: $757.9M$757.9MQ4 202554 holdingsQ1 2026: $759.2M$759.2MQ1 202654 holdingsQ2 2026: $1.1B$1.1BQ2 202658 holdings
Reported 13F value by quarter from the cover pages of this filer (live documents; sub-portfolio reports summed), with holdings listed beneath each bar.
Filing record
Aug 14 2026 13F-HR · period Q2 2026

$1.10B · 58 holdings listed · View original SEC filing ↗
May 15 2026 13F-HR · period Q1 2026

$759.22M · 54 holdings listed · View original SEC filing ↗
Apr 13 2026 13F-HR/A · period Q4 2025

$757.89M · 54 holdings listed · amendment (restatement) · View original SEC filing ↗
Feb 17 2026 13F-HR · period Q4 2025

$757.99M · 54 holdings listed · View original SEC filing ↗
Nov 14 2025 13F-HR · period Q3 2025

$707.32M · 43 holdings listed · View original SEC filing ↗
Aug 15 2025 13F-HR/A · period Q2 2025

$494.14M · 41 holdings listed · amendment (restatement) · View original SEC filing ↗
Aug 14 2025 13F-HR · period Q2 2025

$498.92M · 41 holdings listed · View original SEC filing ↗
Provenance: Cover-page totals from the quarterly 13F reports of this filer on SEC EDGAR; position-level holdings are parsed for tracked managers only. Reporting period: Q2 2026 · latest filing Aug 14, 2026 · Change methodology